Ernst Holler Selected Research

Graft vs Host Disease (Graft-Versus-Host Disease)

1/2022	Low Intestinal IL22 Associates With Increased Transplant-Related Mortality After Allogeneic Stem Cell Transplantation.
1/2022	Prolonged Suppression of Butyrate-Producing Bacteria Is Associated With Acute Gastrointestinal Graft-vs-Host Disease and Transplantation-Related Mortality After Allogeneic Stem Cell Transplantation.
1/2022	Assessment of systemic and gastrointestinal tissue damage biomarkers for GVHD risk stratification.
1/2021	A multicenter prospective, randomized, placebo-controlled phase II/III trial for preemptive acute graft-versus-host disease therapy.
1/2021	An investigation of the diagnostic, predictive, and prognostic impacts of three colonic biopsy grading systems for acute graft versus host disease.
1/2021	Parametric Imaging of Contrast-Enhanced Ultrasound (CEUS) for the Evaluation of Acute Gastrointestinal Graft-Versus-Host Disease.
1/2021	Anti-Thymocyte Globulin Treatment Augments 1,25-Dihydroxyvitamin D3 Serum Levels in Patients Undergoing Hematopoietic Stem Cell Transplantation.
1/2021	Profiling Tissue and Biofluid miR-155-5p, miR-155*, and miR-146a-5p Expression in Graft vs. Host Disease.
1/2021	GPR Expression in Intestinal Biopsies From SCT Patients Is Upregulated in GvHD and Is Suppressed by Broad-Spectrum Antibiotics.
12/2020	Biomarker-guided preemption of steroid-refractory graft-versus-host disease with α-1-antitrypsin.

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Ernst Holler Research Topics

Disease

77	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2022 - 09/2002
22	Bronchiolitis Obliterans Syndrome 03/2021 - 02/2006
16	Infections 01/2021 - 03/2002
15	Neoplasms (Cancer) 11/2021 - 02/2007
10	Inflammation (Inflammations) 01/2022 - 01/2007
10	Leukemia 11/2019 - 02/2006
8	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 11/2007
7	Crohn Disease (Crohn's Disease) 01/2015 - 08/2004
6	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 03/2002
6	Primary Myelofibrosis (Myelosclerosis) 01/2019 - 02/2007
5	Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive) 01/2013 - 11/2002
4	Pneumonia (Pneumonitis) 01/2021 - 08/2004
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2022 - 07/2008
3	Hodgkin Disease (Hodgkin's Disease) 01/2021 - 01/2016
3	Multiple Myeloma 11/2019 - 02/2007
3	Necrosis 02/2014 - 12/2004
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 06/2010 - 04/2007
3	Hemolytic Anemia 02/2006 - 11/2002
2	Communicable Diseases (Infectious Diseases) 01/2021 - 10/2003
2	Colitis 01/2021 - 01/2018
2	Polyneuropathies (Polyneuropathy) 01/2021 - 01/2012
2	Nephritis 09/2020 - 11/2019
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2017 - 05/2009
2	Lymphoma (Lymphomas) 01/2016 - 12/2009
2	Hematologic Diseases (Blood Diseases) 01/2016 - 01/2012
2	Sepsis (Septicemia) 10/2013 - 07/2004
2	Neutropenia 01/2011 - 03/2002
2	Thrombocytopenia (Thrombopenia) 01/2007 - 11/2002
2	Fever (Fevers) 07/2006 - 03/2002
2	Lung Injury 03/2005 - 08/2004
2	Thrombosis (Thrombus) 09/2004 - 11/2002
1	Neoplasm Metastasis (Metastasis) 11/2021
1	Myasthenia Gravis 01/2021
1	Carcinogenesis 12/2020
1	Vasculitis (Vasculitides) 09/2020
1	Pathologic Complete Response 01/2020
1	Dysbiosis 01/2020
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2020

Drug/Important Bio-Agent (IBA)

11	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2006
9	SteroidsIBA 03/2021 - 02/2006
5	CytokinesIBA 08/2005 - 03/2002
4	Proteins (Proteins, Gene)FDA Link 03/2021 - 02/2010
4	Biological ProductsIBA 02/2011 - 09/2002
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2010 - 03/2002
4	DNA (Deoxyribonucleic Acid)IBA 02/2010 - 08/2004
3	Busulfan (Busulfex)FDA Link 01/2022 - 12/2009
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 01/2018
3	Thomsen-Friedenreich antibodiesIBA 02/2020 - 09/2009
3	GlobulinsIBA 02/2020 - 09/2009
3	fludarabineIBA 01/2020 - 07/2008
3	NucleotidesIBA 08/2015 - 07/2007
3	Methotrexate (Mexate)FDA LinkGeneric 10/2012 - 09/2004
3	Imatinib Mesylate (Gleevec)FDA Link 01/2011 - 04/2007
3	Interleukin-6 (Interleukin 6)IBA 06/2010 - 03/2002
3	NF-kappa B (NF-kB)IBA 09/2007 - 08/2004
3	AntigensIBA 02/2007 - 11/2005
2	treosulfanIBA 01/2022 - 01/2020
2	Volatile Fatty AcidsIBA 01/2022 - 01/2021
2	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 01/2021 - 12/2016
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2020 - 11/2002
2	LigandsIBA 01/2018 - 08/2005
2	Anti-Bacterial Agents (Antibiotics)IBA 05/2017 - 05/2014
2	Antimicrobial PeptidesIBA 01/2017 - 08/2011
2	Hemoglobins (Hemoglobin)IBA 02/2016 - 01/2007
2	Toll-Like Receptors (Toll-Like Receptor)IBA 08/2015 - 03/2010
2	C-Reactive ProteinIBA 01/2015 - 07/2006
2	Bacterial DNAIBA 02/2014 - 08/2011
2	Pharmaceutical PreparationsIBA 05/2013 - 10/2010
2	CreatinineIBA 10/2012 - 12/2011
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 10/2012 - 09/2009
2	ChemokinesIBA 02/2011 - 04/2009
2	Interleukin-10 (Interleukin 10)IBA 06/2010 - 12/2004
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 06/2010 - 03/2002
2	InterleukinsIBA 12/2004 - 09/2002
2	Interferon-gamma (Interferon, gamma)IBA 12/2004 - 11/2002
1	Interleukin-22 (IL-22)IBA 01/2022
1	Butyrates (Butyrate)IBA 01/2022
1	Type I Tumor Necrosis Factor ReceptorsIBA 01/2022
1	heparanaseIBA 11/2021
1	EnzymesIBA 11/2021
1	Abatacept (Orencia)FDA Link 03/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	letermovirIBA 01/2021
1	tocilizumab (atlizumab)FDA Link 04/2020
1	Fluticasone (Cutivate)FDA LinkGeneric 02/2020
1	montelukast (Singulair)FDA Link 02/2020
1	Azithromycin (Zithromax)FDA LinkGeneric 02/2020
1	Rituximab (Mabthera)FDA Link 10/2019

Therapy/Procedure

42	Stem Cell Transplantation 01/2022 - 11/2002
41	Hematopoietic Stem Cell Transplantation 01/2021 - 07/2004
20	Therapeutics 01/2021 - 10/2003
19	Transplantation 01/2022 - 11/2002
15	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2017 - 05/2004
14	Cell Transplantation 01/2022 - 07/2008
7	Homologous Transplantation 11/2019 - 07/2011
6	Drug Therapy (Chemotherapy) 01/2021 - 03/2002
4	Salvage Therapy 03/2021 - 10/2012
1	Withholding Treatment 01/2020
1	Donor Selection 11/2019
1	Renal Replacement Therapy (Therapies, Renal Replacement) 11/2019